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pm-226

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
PM226
PM 226
T378151949726-13-9
Potent and selective CB2 receptor agonist (Ki = 12.8 nM; EC50 = 38.67 nM). Exhibits negligible affinity for the CB1 receptor (Ki > 40,000 nM) and no activity at the GPR55. Suppresses neuroinflammation by reducing microglial activation in a multiple sclerosis mouse model. BBB permeable; anti-inflammatory and neuroprotective.
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6-8 weeks
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