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pkm2in1

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
PKM2-IN-1
PKM2 inhibitor, compound 3k
T417094164-88-2
PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 μM, while the IC50 for PKM1 is 4-5 times higher.
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TargetMol | Citations Cited
PKM2-IN-10
T207198
PKM2-IN-10 is a PKM2 inhibitor. It effectively suppresses the proliferation of A549 and HCC1833 cell lines with IC50 values of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 demonstrates antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. It is applicable for research in lung cancer.
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