phloretin

Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.

Phloretin 3',5'-Di-C-glucoside is a useful organic compound for research related to life sciences and the catalog number is T124963.

4'-O-(6-O-Feruloylglucopyranosyl)phloretin is a useful organic compound for research related to life sciences. The catalog number is T125389 and the CAS number is 2058292-99-0.

2′-O-Methylphloretin (compound 3), a flavonoid derivative, extracted from Melodorum siamensis leaves, has demonstrated the ability to inhibit tumor cell line replication [1].

4-Hydroxyphenylpropionylglycine, a metabolite derived from the conditionally essential amino acid tyrosine, is synthesized through a process involving aromatic amino acid aminotransferase and tyrosine aminotransferase activities, with subsequent modifications by gut microbiota and glycine conjugation. Additionally, it serves as a metabolite of the phenol phloretin.