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Results for "
pf-06260933
" in TargetMol Product Catalog- Inhibitors & Agonists3
PF-06260933
PF-6260933, PF 6260933, PF6260933
T42211811510-56-1
PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.
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PF-06260933 HCl
PF06260933 dihydrochloride,PF-06260933 dihydrochloride,PF 06260933 dihydrochloride
T339451883548-86-4
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).
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PF 06260933 dihydrochloride
T36016
MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active. Ammirati et al (2015) Discovery of an in vivo tool to establish proof-of-concept for MAP4K4-based antidiabetic treatment. ACS Med.Chem.Lett. 6 1128 PMID:26617966
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