peptidyl transferase

T-2 Toxin (T-2 Mycotoxin) is a fungal secondary metabolite produced by various Fusarium species in feed and grains, which is highly toxic to reproduction and induces a variety of cardiovascular toxicities.T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis. T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis, induces TM4 cell dysfunction via ROS-induced apoptosis, inhibits DNA and RNA synthesis, and increases hepatic lipid peroxidation levels.

Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase.