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p110δ-in-1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
P110δ-IN-1
PWT-143
T164221595129-71-7
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
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Alpelisib hydrochloride
BYL-719 hydrochloride
T141911584128-91-5
Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties[1][2]. As a potent and selective PI3Kα inhibitor with high oral bioavailability, it has IC50 values of 5 nM for p110α, 250 nM for p110γ, 290 nM for p110δ, and 1200 nM for p110β, indicating its efficacy in targeting enzymes involved in cancer cell proliferation.
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1-2 weeks
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PI3K-IN-51
T871572055765-77-8
PI3K-IN-51, characterized as a PI3K inhibitor, exhibits IC50 values below 500 nM for p120γ and p110δ p85α (WO2016204429A1; Example 10) [1].
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10-14 weeks
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