p.aeruginosa

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting

Blasticidin S HCl is a natural product and an inhibitor of protein synthesis. Blasticidin S HCl is a broad-spectrum antibiotic that can inhibit the cell growth of prokaryotes, fungi, plants and mammalian cells.

Antibacterial agent 114 (compound 1) is a potent antibacterial agent with MIC values of 625 μM for P. aeruginosa, B. subtilis, E. coli, E. faecalis, and S. typhimurium; and 1250 μM for S. mutans and S. aureus microorganisms, respectively [1].

Antibacterial agent 113 was an effective antimicrobial agent (antibacterial) against P. aeruginosa, S. mutans, B. subtilis, E. coli, E. faecalis, S. typhimuriumand and S. aureus microorganisms exhibited antibacterial effects with MIC values of 15625 μM.

Antibacterial agent 112 (compound 2) is a potent antibacterial agent with a minimum inhibitory concentration (MIC) of 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, and S. aureus microorganisms. A3N19 is an HIV-1 antibody with antibacterial activity.