or1896

OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.OR-1896 can be used to study heart failure and vascular dysfunction. OR-1896 can be used to study heart failure and vascular dysfunction.

OR-1896-d3 is the deuterium-labeled form of OR-1896, which is the active, long-lasting metabolite of Levosimendan. It acts as a highly selective phosphodiesterase (PDE III) inhibitor and serves as a potent vasodilator. OR-1896 is capable of opening ATP-sensitive K+ channels and demonstrates Ca2+ sensitizing effects, which help reduce apoptosis in myocardial cells, cardiac remodeling, and myocardial inflammation.