octadecane

Octadecane is a natural product.

1,12-Octadecanediol is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Octadecane (Standard) is a reference standard for octadecane, suitable for quantitative analysis, quality control, and biochemical research. Octadecane is an alkane capable of storing thermal energy as a phase change material at ambient temperatures.

DL-1,3-Dihydroxy-2-amino-octadecane is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

(12R)-1,12-Octadecanediol ((12R)-Octadecane-1,12-diol) is a compound characterized by an 18-carbon straight chain and two hydroxyl groups (C18H38O2). This colorless substance possesses unique properties due to the presence of two hydroxyl groups in its molecular structure. It can be sourced naturally or synthesized chemically and is utilized across various industries. Known for its emollient qualities, it is frequently found in the formulations of cosmetics, personal care products, and pharmaceuticals, where it enhances moisturizing and conditioning effects. The compound's distinctive structure makes it suitable for specific applications in research or industrial processes. In industrial settings, it serves as a valuable chemical intermediate for synthesizing other compounds.

(2S,3S,4R,2'R)-2-(2'-hydroxytetracosanoylamino)octadecane-1,3,4-triol shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom at concentration of 100 ug/mL.

2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra).

Octadecanedioic acid is an endogenous metabolite, is a long-chain dicarboxylic acid.

1-Hydroxyoctadecane (OctadecanolOctadecanol) is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardation, and spasticity, and patients accumulate fatty alcohols such as Octadenol in the plasma and cultured fibroblasts.

Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 μM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft model in a dose-dependent manner. |1. Callmann, C.E., Leguyader, C.L.M., Burton, S.T., et al. Antitumor activity of 1,18-octadecanedioic acid-paclitaxel complexed with human serum albumin. J. Am. Chem. Soc. 141(30), 11765-11769 (2019).

Bis(2,5-dioxopyrrolidin-1-yl) octadecanedioate serves as a linking reagent in organic synthesis [1].

9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the suberin of Quercus suber cork. It plays a role in the composition of plant structures.

1,18-Octadecanediol is a compound derived from Spartium japonicum that acts as a lubricant and reduces cancer in animal studies.

2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.

Hexacyclen is an analogue of 18-crown-6, exhibiting antagonistic and blocking effects on the extracellular calcium-sensing receptor with an EC50 of 20 μM. Possessing multiple secondary amine groups, Hexacyclen serves as an excellent electron donor and functions as a block copolymer.

18-Crown-6-ether (18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane) is an organic compound utilized in forming stable microcapsule responsive layers, which can be further assembled into bilayer microcapsules. For instance, a responsive layer can be prepared using 18-Crown-6-ether and coated with a K+ stabilized G-quadruplex crosslinked hydrogel layer. In the presence of Mg2+ ions, 18-Crown-6-ether and K+ ions can respectively dissociate and lock with the G-quadruplex crosslinked layer, achieving switchable controlled release of the payload.

Hexacyclen, also known as Cycloolefin, is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It serves as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions and functions as an inhibitor for certain diseases like cancer. In biochemistry, Hexacyclen is utilized to selectively bind metal ions within proteins or enzymes, aiding in the study of their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in everyday products or applications.

Hexacyclen (Cycloalkene) is an organic compound characterized by a distinctive macrocyclic structure composed of six nitrogen-containing rings. Known for its metal ion-binding capability, Hexacyclen is frequently employed as a chelating agent in chemistry and biochemistry for selectively binding metal ions in proteins or enzymes to study their structure and function. Additionally, Hexacyclen can serve as a cancer inhibitor.