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nxl104

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Avibactam sodium
AVE-1330A, NXL-104
T42011192491-61-4
Avibactam sodium (NXL-104) is a non-β-lactam β-lactamase inhibitor that inhibits TEM-1, P99, and KPC-2 β-lactamases (IC50=8 80 38 nM) covalently and reversibly. Avibactam sodium has antimicrobial activity and can be used to treat urinary tract infections.
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Avibactam sodium hydrate
NXL-104 hydrate
T607112938989-90-1
Avibactam sodium hydrate (NXL-104 hydrate) is a highly effective β-lactamase inhibitor that inhibits β-lactamases TEM-1 and CTX-M-15, as well as the carbapenemase produced by Klebsiella pneumoniae and carbapenem-resistant Enterobacteriaceae.
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1-2 weeks
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Avibactam sodium dihydrate
T60874
Avibactam sodium (NXL-104) dihydrate inhibits CTX-M-15 and β-lactamase TEM-1 with IC50 values of 5 nM and 8 nM, respectively, and is a reversible covalent inhibitor of non-β-lactam β-lactamase [1].
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10-14 weeks
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Avibactam sodium salt-13C5
TMIJ-0182
Avibactam sodium salt-13C5 is the 13C labeled compound of Avibactam sodium salt. Avibactam sodium salt has a CAS number of 1192491-61-4. Avibactam is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).
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20 days
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AVE-1330A free acid
T69300396731-14-9
AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.
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10-14 weeks
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Avibactam free acid
NXL-104 free acid
T104221192500-31-4
Avibactam (NXL-104) free acid is a covalent, reversible inhibitor of non-β-lactam β-lactamase, with IC50 values of 8 nM for β-lactamase TEM-1 and 5 nM for CTX-M-15.
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7-10 days
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AVE-1330A sodium
T69299396731-20-7
AVE-1330A sodium is a beta-Lactamase inhibitor.
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10-14 weeks
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