nucleophile

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic nature of the imidazole side chain.

Enzyme-IN-1 (compound 1), a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases, specifically targets and inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. This compound may possess potential anti-inflammatory properties [1].

Intermediate and building block - nucleophile (amine)

Heterocyclic compound-pyridine, intermediate and building block-nucleophile

Other heterocyclic compound - pyrrolidine, building block - electrophile and nucleophile

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine is a highly pure biochemical reagent that can be used in biological chemistry experiments and drug synthesis research.

Intermediates and building blocks - phosphorous compounds; nucleophile

Heterocyclic Compounds - Pyrimidine; Intermediate and Building Blocks - Nucleophile; Nucleoside base;Intermediate and Building Blocks----- Electrophiles

Heterocyclic Compounds –Triazine; Intermediates and Building Blocks - Nucleophile; Nucleoside base

Intermediate and Building Blocks - Nucleophile; Scaffolds and Templates

Intermediates and Building Blocks - Nucleoside base, Electrophile, Nucleophile; Heterocyclic Compounds - Pyridine; Scaffolds and Templates

Intermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocyclic Compounds - Pyrimidine; Scaffolds and Templates

5-(2-Hydroxyethyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.

5-(2-Hydroxyethyl)-2-thiouracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.

5-(3-Hydroxypropyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.

Intermediates and Building Blocks - Nucleophile, Electrophile; Fine Chemical

Intermediates and Building Blocks - Nucleophile; Fine Chemicals

(R)-Tetrahydro-2H-pyran-2-ol bolongs toIntermediates and Building Blocks - Nucleophile.

(S)-Tetrahydro-2H-pyran-2-ol bolongs toIntermediates and Building Blocks - Nucleophile.

NH-bis(PEG8-OH) is a bifunctional reagent comprising two alcohol groups linked by a secondary amine. The alcohol groups can react with carboxylic acids to form esters, while the secondary amine serves as a nucleophile, allowing it to connect with ketones, aldehydes, and carboxylic acids. The PEG spacer confers water solubility, potentially altering the molecule's DMPK properties.