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Results for "
nsc109555
" in TargetMol Product Catalog- Inhibitors & Agonists2
NSC 109555
NSC-109555,DDUG dimethanesulfonate,NSC109555,DDUG diMS
T3373715427-93-7
NSC 109555 is a selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 μM). Inhibits histone H1 phosphorylation (IC50 = 0.24 μM) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo.
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