Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Apoptosis
    (1)
  • Ras
    (1)
  • Rho
    (1)
Filter
Search Result
Results for "

nsc-23766 trihydrochloride

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1
    TargetMol | Inhibitors_Agonists
NSC 23766 trihydrochloride
T63421177865-17-6
NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
  • Inquiry Price
Size
QTY
TargetMol
NSC 23766
NSC23766
T40848733767-34-5
NSC 23766 is a Rac1 GTPase inhibitor that inhibits Rac1 activation by targeting guanine nucleotide exchange factors (GEFs), while it has no inhibitory effect on the closely related targets Cdc42 and RhoA, affecting the cell cycle and inhibiting cell proliferation in a dose-dependent manner. It also regulates endothelial NO synthase expression and endothelial function, and inhibits platelet aggregation and γ-secretase activity.NSC23766 competitively inhibits M2 muscarinic acetylcholine receptor (M2 mAChR)-induced Rac1 activation in neonatal rat cardiomyocytes.
  • Inquiry Price
7-10 days
Size
QTY