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nod1 antagonist-2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
NOD1 antagonist-2
T204149
NOD1antagonist-2 (compound 66) is an orally active and selective inhibitor that can suppress NOD1 in both humans and mice. It effectively blocks the NOD1-induced NF-κB and MAPK pathways.
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nod1/2 antagonist-1
T724732704623-69-6
NOD1 2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1 2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibits an acceptable half-life (T1 2) of 67.6 minutes. Additionally, NOD1 2 Antagonist-1 enhances the antitumor efficiency of Paclitaxel (PTX).
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10-14 weeks
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