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By Target- Epoxide Hydrolase
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Results for "
nanosuspension
" in TargetMol Product Catalog- Inhibitors & Agonists2
N,N'-Dicyclohexylurea
DCU, Dicyclohexylurea, Dicyclohexylcarbodiamide, NSC 17013, 1,3-Dicyclohexylurea
T230442387-23-7
N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor.
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ELND006
T709511333990-84-3
ELND006 is a novel gamma secretase inhibitor previously under investigation for the oral treatment of Alzheimer's disease. ELND006 shows poor solubility and has moderate to high permeability. The in vivo performance of the ELND006 nanosuspension was tested in fed and fasted beagle dogs and compared with a gelatin capsule containing reference API. The results show that nanosizing ELND006 profoundly improved the oral bioavailability and virtually eliminated variation resulting from food intake.
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