my-101

AMY-101 acetate (Cp40 acetate) is a cyclic peptide, an inhibitor of C3 Complement and an immunomodulator used in the treatment of gingivitis and periodontitis, which significantly reduces inflammation and lowers MMP-8 and MMP-9 levels.AMY-101 acetate also have a palliative effect on covid -19-induced lung inflammation injury and SARS-COV-2-related acute kidney injury in patients with acute respiratory distress syndrome (ARDS).

AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.

AMY-101 TFA is a cyclic peptide that acts as an inhibitor of complement C3 and an immunomodulator, used for the treatment of gingivitis and periodontitis. It significantly reduces inflammation and lowers levels of MMP-8 and MMP-9. AMY-101 TFA also has a mitigating effect on lung inflammation damage in patients with COVID-19-induced ARDS and acute kidney injury associated with SARS-CoV-2.