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mpt0e 028

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Imofinostat
TMU-C-0012, TMUC0012, MPT0E028, ABT-301, ABT301
T161311338320-94-7
Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells. In B-cell lymphoma, Imofinostat induces cell cycle arrest and apoptosis whilst inhibiting Akt phosphorylation, demonstrating anticancer activity across multiple tumour types.
  • $88
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