mollugin

Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.

3-Hydroxymollugin is a useful organic compound for research related to life sciences and the catalog number is T125745.

Furomollugin has antiviral activity, it can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 = 2.0 micrograms mL, in human hepatoma Hep3B cells.

3-Methoxymollugin is a natural phenolic compound found in several plants, including the Chinese herb Mollugo pentaphylla. It has a variety of uses in the medical, food and cosmetic industries. It has been found to have anti-inflammatory, antioxidant, antibacterial and antitumor activities.