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(2)
By Target- HIF/HIF Prolyl-Hydroxylase
- Drug Metabolite(1)
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Results for "
molidustat
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Cell Research1
Molidustat
Cited
BAY 85-3934
T26521154028-82-6
Molidustat (BAY 85-3934)(BAY-85-3934), an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH), stimulates erythropoietin (EPO) production and the formation of red blood cells.
- $45
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CitedMolidustat glucuronide
BAY-348
TYD-029642230205-31-7
Molidustatglucuronide (BAY-348) is the N-glucuronide metabolite of Molidustat. Primarily formed through glucuronidation, it is the sole metabolite of Molidustat present in human and animal plasma. Molidustat glucuronide is utilized in the study of Molidustat's metabolic pathways and pharmacokinetic properties.
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Molidustat sodium
T888121375799-59-9
Molidustat sodium (5 μM; 20 min) is sufficient to induce detectable levels of HIF-1α in HeLa cells. In a cellular reporter assay, the compound stimulates the expression of the luciferase reporter gene under the control of a hypoxia-responsive element promoter, with an average (± SD) EC50 of 8.4 μM (n=4).
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