Home Tools
Log in
Cart

Search Result

Search Results for " misfolding "

9

Compounds

Cat No. Product Name Synonyms Targets
T9174 Icerguastat Sephin 1,lcerguastat,IFB-088 Phosphatase
Icerguastat (IFB-088) is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo.
T21824 Sephin1 NSC 65390,IFB-088 Phosphatase
Sephin1 (IFB-088) is reportedly a selective inhibitor of GADD34 (PPP1R15A), which is a stress-induced regulatory subunit of protein phosphatase 1 complex that dephosphorylates eIF2α
T62304 Minzasolmin (R)-NPT200-11,UCB0599,DLX-313 Others
Minzasolmin(DLX-313) is an alpha-synuclein misfolding inhibitor for the study of Parkinson's disease.
T29097 VAS 3947 VA-S3947,VA S3947,VAS3947 Apoptosis , NADPH-oxidase
VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to protein aggregation and misfolding, independent of anti-NOX act...
T111959 IFB-088 acetate
IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein...
T27314 Fe-TMPyP
Fe-TMPyP binds to the prion protein PrP and inhibits misfolding. Fe-TMPyP is also a peroxynitrite decomposition catalyst.
T60042 NPT200-11 Others
NPT200-11 is an orally bioavailable and brain penetrating inhibitor of accumulation of alpha-synuclein (ASYN) misfolding and aggregation. NPT200-11 can be used in studies about the underlying pathology of synucleinopathi...
T23210 Quinacrine (dihydrochloride hydrate) Quinacrine (hydrochloride hydrate) (83-89-6 free base) Others
Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM) and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of pr...
T36499 CuATSM
The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding ...
TargetMol