9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19720 | Colcemid | C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine | Microtubule Associated |
Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning. | |||
T0190 | Vinorelbine | KW-2307 base | Microtubule Associated |
Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase. | |||
T9657 | FiVe1 | Others | |
FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selec... | |||
T27891 | LY195448 HCl | LY195448,UNII-BR0DFE3GF6,LY-195448 | |
LY195448 HCl is a phenethanolamine shown anti-tumour activity. It blocks cells at metaphase. | |||
T69433 | Myrmicacin | ||
Myrmicacin is an inhibitor of mitotic progression after metaphase. | |||
T70628 | Cmpd-A | ||
Cmpd-A is a time-dependent CENP-E inhibitor with potent antitumor activity. Cmpd-A inhibits the ATPase activity of the CENP-E motor domain, acting as a time-dependent inhibitor with an ATP-competitive-like behavior. Cmpd... | |||
T82406 | FF-MAS | ||
FF-MAS is a potent agonist that enhances the meiotic maturation and preimplantation development of mouse oocytes cultured in vitro. It facilitates progression to metaphase II (MII) and augments the oocytes' ability to ad... | |||
T36979 | Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt) | Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt) | |
Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3... | |||
T71252 | PC-046 | ||
PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory acti... |