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Results for "
mcl-1 antagonist 1
" in TargetMol Product Catalog- Inhibitors & Agonists5
- Peptide Products1
Mcl-1 antagonist 1
T119672376775-05-0
Mcl-1 antagonist 1 is an inhibitor of the Mcl-1 protein.
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Motixafortide TFA(664334-36-5,Free)
TF 14016 TFA, T140 TFA, BL-8040 TFA, BKT140 TFA
T14665L
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ～1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a 16-1 expression.
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(+)-Apogossypol
Apogossypol, NSC736630
T1345966389-74-0
(+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively).
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Mcl-1 inhibitor 20
T200183
Mcl-1 inhibitor20 (compound 47) is an Mcl-1 antagonist with anti-leukemia properties. It binds to the BH3 docking groove of Mcl-1 (Ki=24 nM), occupies the P1 pocket, and interacts with Lys234 and Val249. Mcl-1 inhibitor20 also exhibits good microsomal stability, favorable pharmacokinetic properties, and low cardiotoxicity.
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UNBS-1450
UNBS 1450,UBS1450,UBS-1450,UBS 1450
T29060676541-58-5
UNBS-1450 is a sodium channel antagonist. UNBS-1450 is a hemi-synthetic cardenolide derived from 2″-oxovorusharin, it is effective against various cancer cell types with an excellent differential toxicity. At low nanomolar concentrations, UNBS-1450 induce
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