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malpeg4acid

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Mal-PEG4-acid
T15989518044-41-2
Mal-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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    3,4-Dibromo-Mal-PEG4-Acid
    TYD-020222434639-17-3
    3,4-Dibromo-Mal-PEG4-Acid is a site-specific ADC linker featuring a dibromomaleimide group and an acid group. The presence of two bromine atoms in the dibromomaleimide group allows for two substitution points. In the presence of EDC and HATU, the carboxylic acid can react with primary amines to form stable amide bonds. The hydrophilic PEG linker enhances the compound's solubility in aqueous media.
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    10-14 weeks
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