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macrosphelide a

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
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    TargetMol | Natural_Products
(+)-Macrosphelide A
T37552172923-77-2
(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectively), but not Gram-negative bacteria or fungi.
  • $1,170
35 days
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Macrosphelide L
TN10892431935-18-1
Macrosphelide L is an inhibitor of cell adhesion. It prevents HL-60 cells from adhering to HU-VEC cells, with an IC50 of 5.6 μM.
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10-14 weeks
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