lupanine

Lupanine ((+)-Lupanine), a naturally occurring quinolizidine alkaloid, potently affinity and activates nicotinic acetylcholine receptor (nAChR) (Ki=500 nM), and shows significant neuroprotection against soluble amyloid β-oligomers (SO-Aβ) toxicity in cellular models in association with the anti-apoptotic PI3K Akt Bcl-2 signaling pathway with anti-Alzheimer's disease potential. Improves glucose homeostasis by affecting KATP channels and enhancing insulin secretion with therapeutic potential for type 2 diabetes.

Lupanine hydrochloride, a natural ketonic derivative of Sparteine ((+)-Sparteine), exhibits ganglioplegic activity and binds to the nicotinic receptor (nAChR) with a K i value of 500 nM [1].

alpha-Isolupanine is a useful organic compound for research related to life sciences and the catalog number is T124791.

α-Isolupanine, an alkaloid found in Narrow-Leafed Lupin (Lupinus angustifolius L.), can be isolated for the study of anthracnose [1].

13β-Hydroxylupanine, a natural product, is present in Caulophyllum robustum Maxim [1].

13-Hydroxylupanine, a characteristic alkaloid of sweet lupins, inhibits ganglionic transmission, reduces cardiac contractility, and induces contraction of uterine smooth muscle [1].

13-Hydroxylupanine is a natural product from Cytisus scoparius.