losartan (d-4 carboxylic acid)

Losartan (D4 Carboxylic Acid) is the deuterium labeled Losartan (TMSM-3475), which is an angiotensin II receptor antagonist.

Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), produces a depressor response and vasodilatation. As a metabolite of losartan, it is more potent than losartan in blocking angiotensin II-induced responses in vascular smooth muscle cells.

Losartan (DuP-753) is an angiotensin II receptor antagonist.

Losartan D4 (Standard) is a reference standard of Losartan D4 intended for quantitative analysis, quality control, and related biochemical research applications. Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).

Losartan-D4 is a deuterated isotope of Losartan (T0215L) for isotopic tracing. Losartan (T0215L) is an angiotensin II receptor antagonist (IC50=20 nM).

Losartan potassium (DuP-753 potassium), an Angiotensin II Receptor Blocker, selectively and competitively inhibits the binding of angiotensin II to the angiotensin I (AT1) receptor.

Losartan (D4 Carboxylic Acid) (Standard) is a reference standard of Losartan (D4 Carboxylic Acid) intended for quantitative analysis, quality control, and related biochemical research applications.

Losartan potassium (Standard) is a reference standard for research and analysis in studies involving Losartan potassium. Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.

Losartan-D3 Carboxylic Acid is the deuterated form of Losartan Carboxylic Acid (TMSM-3475). Losartan acts as an antagonist to the angiotensin II receptor, competitively binding to the AT1 receptor with an IC50 of 20 nM.