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Results for "
leptomycin a
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Natural Products1
Leptomycin A
T1183787081-36-5
Leptomycin A, a metabolite derived from Streptomyces, acts as an inhibitor of CRM1 (exportin 1) and effectively suppresses HIV-1 replication. Compared to Leptomycin B, it exhibits lesser potency. Leptomycin A hampers the interaction between CRM1 and nuclear export signals, effectively hindering the nuclear export of a wide array of proteins.
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