Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Others
    (2)
Filter
Search Result
Results for "

l moses dihydrochloride

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
L Moses dihydrochloride
T36109
High affinity and selective cell-permeable p300/CBP-associated factor (PCAF) inhibitor (Ki = 47 nM). Exhibits no significant activity against a panel of 48 other bromodomains except GCN5 (Kd = 600 nM). Exhibits >4500-fold selectivity for PCAF over BRD4. Also exhibits metabolic stability in mouse and human liver microsomes and no observable cytotoxicity in peripheral blood mononuclear cells (PBMC). Moustakim et al (2017) Discovery of a PCAF bromodomain chemical probe. Angew.Chem.Int.Ed. 56 827 PMID:27966810
  • TBD
35 days
Size
QTY
l-moses dihydrochloride
T62424
L-Moses (L-45) dihydrochloride is the first potent and selective inhibitor of the p300 CBP-associated factor (PCAF) bromodomain (Brd) with a dissociation constant (Kd) of 126 nM.
  • $4,528
10-14 weeks
Size
QTY