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krn 2

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
KRN2
T11781248260-75-5
KRN2 has potential to treat NFAT5-mediated Chronic Arthritis. KRN2 is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 100 nM.
  • $1,520
1-2 weeks
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KRN2 bromide
T117821390654-28-0In house
KRN2 bromide is a potent, selective inhibitor of nuclear factor of activated T cells (NFAT5, IC50= 0.1 μM).
  • $35
In Stock
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α-GalCer analog 8
α-GalCer analog 8,α-Galactosylceramide analog 8
T35450922727-14-8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.
  • $592
35 days
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