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kmd-3213

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Silodosin
KMD 3213, KAD 3213
T1504160970-54-7
Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.
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Silodosin-d4
TMID-06371426173-86-5
Silodosin-d4 is the deuterated form of Silodosin. Silodosin (KAD 3213; KMD 3213) is a potent, selective, orally active α1A-adrenergic receptor (α1A-AR) antagonist. It exhibits high affinity for α1A-AR with a Ki of 0.036 nM, which is 162 and 50 times stronger compared to its affinities for α1B-AR and α1D-AR, with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent used in the research of LUTS/BPH.
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