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(2)
By Target- Histone Acetyltransferase
- Apoptosis(1)
- STAT(1)
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Results for "
kat3b
" in TargetMol Product Catalog- Inhibitors & Agonists2
L002 
T11807321695-57-2
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By blocking histone acetylation, p53 acetylation, and STAT3 activation, L002 shows potential in the treatment of hypertension‐induced cardiac hypertrophy and fibrogenesis.
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