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js25

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
JS25
T696462411771-95-2
JS25 is a selective, covalent BTK inhibitor that deactivates BTK by chelating Tyr551, exhibiting an IC50 of 5.8 nM. It suppresses cancer cell proliferation, induces pronounced cell death, and enhances Burkitt's lymphoma murine xenograft model outcomes. Importantly, JS25 efficiently penetrates the blood-brain barrier.
  • $1,670
6-8 weeks
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