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Results for "
jnj10198409
" in TargetMol Product Catalog- Inhibitors & Agonists1
JNJ-10198409
JNJ-10198409
T15616627518-40-5
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
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