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By Target- Apoptosis
- Aurora Kinase(1)
- CDK(1)
- Others(1)
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Results for "
jnj-7706621
" in TargetMol Product Catalog- Inhibitors & Agonists2
JNJ-7706621
JNJ 7706621
T6126443797-96-4
JNJ-7706621 is a potent aurora kinase inhibitor that also inhibits CDK1 and CDK2.
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3-Methylthienyl-carbonyl-JNJ-7706621
T40546443798-09-2
3-Methylthienyl-carbonyl-JNJ-7706621 is a highly potent and selective inhibitor of cyclin-dependent kinase (CDK), showing IC50 values of 6.4 nM for CDK1 cyclin B and 2 nM for CDK2 cyclin A. It also exhibits potent inhibition of GSK-3 (IC50 = 0.041 μM) and moderate inhibition of CDK4, VEGF-R2, and FGF-R2 (IC50 = 0.11 μM, 0.13 μM, and 0.22 μM, respectively), making it significant for cancer research.
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