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By Target- EGFR
- PROTACs(2)
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- NF-κB(1)
- NO Synthase(1)
- Opioid Receptor(1)
- ROS(1)
- TLR(1)
- p38 MAPK(1)
- Others(1)
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Results for "
jf 1
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products2
Nalmefene
TH-104, ORF11676, ORF 11676, JF-1, JF1, AV-104
T8695455096-26-9
Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used in the study of opioid overdose and alcohol dependence.
- $30
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QTY
SJF 1528
T362452230821-38-0
Potent EGFR Degrader (DC50 values are 39.2 nM for wild-type EGFR in OVCAR8 cells and 736 nM for Exon20Ins mutated EGFR in HeLa cells). Also degrades HER2. Comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Inhibits proliferation of HER2-driven breast cancer cell lines (IC50 = 102 nM for SKBr3 cells).
- $1,430
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