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By Target- EGFR
- JAK(1)
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Results for "
jbj 04 125 02
" in TargetMol Product Catalog- Inhibitors & Agonists2
JBJ-04-125-02
T117142060610-53-7
JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R T790M C797S signaling. JBJ-04-125-02 has anti-tumor activities. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858
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QTY
(Rac)-JBJ-04-125-02
JBJ-04-125-02
T88722140807-05-0
(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.
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