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(2)
By Target- JAK
- Drug Metabolite(1)
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Results for "
janex1
" in TargetMol Product Catalog- Inhibitors & Agonists3
JANEX-1
WHI-P131, Jak3 inhibitor I
T2045202475-60-3
JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.
- $30
Size
QTY
JANEX-1-M
JANEX1M, JANEX 1 M, 7-O-DEMETHYLJANEX-1
T202764406484-24-0
JANEX-1 is a JAK inhibitor metabolized by cytochrome P450 enzymes CYP1A1 and CYP1A2. The formation of JANEX-1-M follows Michaelis-Menten kinetics when in the presence of CYP1A1 and CYP1A2 expressed via baculovirus.
- Inquiry Price
Size
QTY
JANEX-1 hydrochloride
WHI-P131 hydrochloride, Jak3 inhibitor I hydrochloride
T88730188829-39-2
JANEX-1 (WHI-P131) hydrochloride is an effective and specific JAK3 inhibitor with a Ki of 2.3 μM and an IC50 of 78 μM. It does not inhibit JAK1 and JAK2.
- $1,520
Size
QTY
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