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irucaparib ap6

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
  • PROTAC Products
    3
    TargetMol | PROTAC
irucaparib-ap6
T137372410557-00-3
iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.
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Thalidomide-NH-PEG7
T18814
Thalidomide-NH-PEG7 is a synthesized conjugate of an E3 ligase ligand and linker, intended for use in antibody-drug conjugates (ADCs). It can be attached to a protein ligand via a linker to form PROTAC iRucaparib-AP6, a highly selective degrader of PARP1[1].
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NH2-PEG7
T163171425973-14-3
NH2-PEG7 is a para-aminomethylbenzyloxycarbonyl (PROTAC) linker compound consisting of a polyethylene glycol (PEG) chain. It finds application in the synthesis of the PROTAC PARP1 degrader called iRucaparib-AP6[1].
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7-10 days
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