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(2)
By Target- IDO
- Indoleamine 2,3-Dioxygenase (IDO)(2)
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Results for "
ido in 8
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein1
IDO-IN-8
NLG-1487
T116211402837-77-7
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).
- $1,190
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IDO1/TDO-IN-8
T207127
IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.
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