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Results for "
hypocholesterolemia
" in TargetMol Product Catalog- Inhibitors & Agonists2
AY 9944
T14362366-93-8In house
AY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 also inhibits sterol Δ7-Δ8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3β-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
- $35
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Carboxylesterase-IN-5
T212166648894-93-3
Carboxylesterase-IN-5 (Compound 2e) is an irreversible competitive inhibitor of carboxylesterase (CES) with an IC50 of 21.7 nM for porcine liver CES. It is applicable in studies related to hypocholesterolemia.
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