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hydroxypropyl beta cyclodextrin

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  • Inhibitors & Agonists
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Hydroxypropyl-beta-cyclodextrin
HP-beta-CyD,VTS-270,HP-beta-CD,Hydroxypropyl-beta-cyclodextri,THPB,HPbCD
T27563107745-73-3
Hydroxypropyl-beta-cyclodextrin, also known as Hydroxypropyl-beta-cyclodextrin; THPB; HP-beta-CD; HPbCD; HP-beta-CyD; VTS-270; HPbetaCD; HPbetaCyD, is a drug candidate potentially for the treatment of Niemann-Pick type C diseases. In April 2009, hydroxypr
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HP-β-CD
Hydroxypropyl-β-cyclodextrin, Hydroxypropyl betadex
T19609128446-35-5
HP-β-CD (HP-β-CD) is a widely used drug delivery vehicle to improve stability and bioavailability.
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PX-316
T69589253440-95-8
PX-316 is a AKT inhibior. PX-316, when administered intraperitoneally to mice at 150 mg kg, inhibits Akt activation in HT-29 human tumor xenografts up to 78% at 10 h with recovery to 34% at 48 h. PX-316 has antitumor activity against early human MCF-7 breast cancer and HT-29 colon cancer xenografts in mice. PX-316 formulated in 20% hydroxypropyl-beta-cyclodextrin for intravenous administration is well tolerated in mice and rats with no hemolysis and no hematological toxicity. Thus, PX-316 is the lead compound of a new class of potential agents that inhibit Akt survival signaling.
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10-14 weeks
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