hydroxocobalamin

Hydroxocobalamin acetate is used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia. Hydroxocobalamin, an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, is approved by the US Food and Drug Administration for the treatment of cyanide toxicity.

Hydroxocobalamin (Vitamin B12a), a member of the vitamin B12 family, is a potent cyanide antidote. It effectively reduces cyanide concentrations in cells and plasma, significantly increasing the survival rate in cases of acute cyanide poisoning. Additionally, Hydroxocobalamin is used to improve the metabolic profile and neurocognitive outcomes associated with newborn Cbl-C defects and can normalize plasma levels in patients with vitamin B12 deficiency. It is also utilized in research concerning metabolic and neurological diseases, though it may be associated with the induction of acute kidney injury (AKI).

Vitamin B12a hydrochloride (Hydroxocobalamin hydrochloride) is the natural active form of vitamin B12 and is an essential water-soluble vitamin.It is commonly used as a cyanide detoxifier and nutritional supplement, and can be administered by injection, inhalation, or orally.