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By Target- Gamma-secretase
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Results for "
hpb
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Isotope Products1
PHPB-d7
(R S)-2-(1-hydroxy-n-pentyl)benzoic acid potassium salt-d7
TMIH-0434
PHPB-d7 is a deuterated compound of PHPB.
- $485
Size
QTY
funalenone
T37713259728-61-5
Funalenone is a phenalenone originally isolated from A. niger. It inhibits HIV-1 integrase (IC50 = 10 μM) and HIV-1 replication in human peripheral blood cells transformed by murine leukemia virus (HPB-M(a); IC50 = 1.7 μM) but is less cytotoxic to mammalian HPB-M(a) cells (IC50 = 87 μM). Funalenone selectively inhibits matrix metalloproteinase-1 (MMP-1; IC50 = 170 μM) over MMP-2 and MMP-9, which it inhibits by 18.3 and 38.2%, respectively, when used at a concentration of 400 μM. It also inhibits the bacterial cell wall synthesis enzymes MraY and MurG (IC50s = 25.5 μM in a membrane plate assay) and inhibits growth of S. aureus with a MIC value of 64 μg mL.
- $533
Size
QTY
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