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hdac8in1

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  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • PROTAC Products
    1
    TargetMol | PROTAC
HDAC8-IN-1
T70821417997-93-3
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].
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HDAC8-IN-11
T891153035977-24-0
HDAC8-IN-11 is a PROTAC target protein ligand.
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HDAC8-IN-10
T89475
HDAC8-IN-10 (compound 15) serves as a potent inhibitor of HDAC8, exhibiting an IC50 value of 7.6 nM. It also acts as a ligand for the HDAC8 target protein, utilized in the synthesis of PROTAC YX862.
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