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(2)
By Target- NO Synthase
- NOS(2)
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Results for "
gw-274150
" in TargetMol Product Catalog- Inhibitors & Agonists2
GW274150
T11518L210354-22-6In house
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.
- $32
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QTY
GW274150 phosphate
GW 274150 phosphate
T11518438542-15-5
GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM in J774 cells. It mitigates experimental renal ischaemia-reperfusion injury and exhibits analgesic effects in rat models of inflammatory and neuropathic pain.
- $99
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