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gsk1842799 hcl

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  • Inhibitors & Agonists
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GSK1842799 HCl
T710691277165-15-7
GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000× selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical.
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8-10 weeks
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MK-1775 hemihydrate
T710671277170-60-1
MK-1775 hemihydrate is a WEE1 inhibitor with potential antineoplastic sensitizing activity.
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6-8 weeks
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