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gsk-3326595

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
GSK3326595
EPZ015938
T57451616392-22-3In house
GSK3326595 (EPZ015938) is an inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50:6.2 nM.).
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Tomivosertib HCl
T701241849590-02-8
Tomivosertib, also known as eFT508 is a MNK1 2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1 2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.
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1-2 weeks
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