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(2)
By Target- Apoptosis
- MEK(2)
- Autophagy(1)
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Results for "
gsk 1120212
" in TargetMol Product Catalog- Inhibitors & Agonists2
Trametinib
Cited
JTP-74057, GSK1120212
T2125871700-17-3
Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7 0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.
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CitedTrametinib (DMSO solvate)
Trametinib DMSO solvate, Trametinib dimethyl sulfoxide, JTP-74057 (DMSO solvate), GSK-1120212 (DMSO solvate)
T58571187431-43-1
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and selective MEK inhibitor that specifically inhibits MEK1 2 (IC50: 2 nM).
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