glycine(standard)

Glycine (Standard) is a reference standard for research and analysis in studies involving glycine. Glycine is an inhibitory neurotransmitter in the central nervous system and a co-agonist of glutamate, enhancing NMDA receptor excitability. It is found in gelatin and silk fibroin and is used as a nutrient in medical treatments.

Fmoc-Gly-OH is the simplest Fmoc-amino acid and is the only standard amino acid without a chiral center, Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.

DL-Alanine (Standard) is the standard substance of DL-Alanine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. DL-Alanine (DL-2-Aminopropionic acid) is an amino acid that is a racemic compound of L- and D-alanine.DL-Alanine is often used as a reducing and capping agent in conjunction with aqueous silver nitrate for nanoparticle generation.DL-Alanine is a sweetening agent, and can be grouped with glycine and sodium saccharin.DL-Alanine plays an important role in glucose-alanine cycling between tissues and liver.DL-Alanine can be used to study the chelation of transition metals such as Cu, Zn, and Cd. DL-Alanine plays an important role in the glucose-alanine cycle between tissues and the liver.DL-Alanine can be used to study the chelation of transition metals such as Cu, Zn, and Cd.

Soyasaponin Ae (Standard) is a reference standard for research and analysis in studies involving Soyasaponin Ae. Soyasaponin Ae (Acetyl-soyasaponin A5), a chemical compound, can be isolated from Glycine max MERRILL seeds [1].

Myristic acid (Standard) is the standard substance of Myristic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Myristic acid (Crodacid) , a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by covalently binding to the N-terminal glycine residues, in a process called N-terminal myristoylation. Myristoylation of substrate proteins by this fatty acid has the potential to activate and mediate many physiological pathways. Furthermore, saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFκB (nuclear factor κB) activation.

Colchicine (Standard) is a reference standard for research and analysis in studies involving Colchicine. Colchicine is an orally active natural alkaloid that acts by inhibiting microtubule polymerization (IC50 = 3 nM) and as a competitive antagonist of the α3 glycine receptor. It possesses broad anti-inflammatory, immunosuppressive, and antifibrotic activities, can inhibit NLRP3 inflammasome activation to prevent NSAID-induced small intestine injury, holds potential for gouty arthritis and rheumatoid arthritis research, and is commonly used to establish Alzheimer’s disease models.

Deoxycholic acid (Standard) is a reference standard for research and analysis in studies involving Deoxycholic acid. Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.

Betaine (Standard) is a reference standard for research and analysis in studies involving Betaine. Betaine (trimethylglycine) is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.

Cholic Acid (Standard) is a reference standard for research and analysis in studies involving Cholic Acid. Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.

Glycocholic acid hydrate (Standard) is a reference standard for research and analysis in studies involving Glycocholic acid hydrate. Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals.

Glycochenodeoxycholic acid sodium salt (Standard) is a reference standard for research and analysis in studies involving Glycochenodeoxycholic acid sodium salt. Glycochenodeoxycholic acid sodium salt is a bile salt formed in the liver from deoxycholic acid and glycine that induces apoptosis in hepatocytes. It acts as a detergent, dissolves fats for absorption, and is itself absorbed.

Glycoursodeoxycholic acid (Standard) is a reference standard for research and analysis in studies involving Glycoursodeoxycholic acid. Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, and almost all bile acids in the bile duct, therefore, exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals.

Glycolithocholic acid (Standard) is a reference standard for research and analysis in studies involving Glycolithocholic acid. Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.

Methyl 2-(1H-indol-3-yl)acetate (Standard) is a reference standard for research and analysis in studies involving Methyl 2-(1H-indol-3-yl)acetate. Methyl 2-(1H-indol-3-yl)acetate is found in apples. it is obtained from sea peas (Lathyrus maritimus), purple beans (Vicia amurensis), wild soybeans (Glycine soja), wild beans (Vigna catiang var. sinensis) and Methyl 2-(1H-indol-3-yl)acetate has antitumor activity.

β-Alanine (Standard) is a reference standard for research and analysis in studies involving β-Alanine. β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.

Hippuric acid (Standard) is a reference standard for research and analysis in studies involving Hippuric acid. Hippuric acid (2-Benzamidoacetic acid) is an acyl glycine formed by the conjugation of benzoic acid with glycine. Hippuric acid) is a normal component of urine and is typically increased with increased consumption of phenolic compounds (tea, wine, fruit juices). These phenols are converted to benzoic acid which is then converted to hippuric acid and excreted in the urine.

N-Isovaleroylglycine (Standard) is a reference standard for research and analysis in studies involving N-Isovaleroylglycine. N-Isovaleroylglycine (Isovaleroylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases, the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. N-Isovaleroylglycine is a byproduct of the catabolism of the amino acid leucine. Accumulation of N-Isovaleroylglycine occurs in Isovaleric Acidemia (IVA).

2-(2-Methylbenzamido)acetic acid (Standard) is a reference standard for research and analysis in studies involving 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Methylhippuric acid is a metabolite of xylene which is an aromatic hydrocarbon widely used as a solvent.

3-Methyl-L-histidine (Standard) is a reference standard for research and analysis in studies involving 3-Methyl-L-histidine. 3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. It is also a biomarker for the consumption of soy products. 3-Methylhistidine is a very strong basic compound (based on its pKa). 3-Methylhistidine exists in all eukaryotes, ranging from yeast to humans. In humans, 3-methylhistidine is involved in methylhistidine metabolism. 3-Methylhistidine, with regard to humans, has been found to be associated with several diseases such as diabetes mellitus type 2, eosinophilic esophagitis, and kidney disease; 3-methylhistidine has also been linked to the inborn metabolic disorder propionic acidemia. The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a product of peptide bond synthesis and methylation of actin and myosin. 3-Methylhistidine is a biomarker for meat consumption, especially chicken.Structure

Sarcosine (Standard) is a reference standard for research and analysis in studies involving Sarcosine. Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.