glutathione

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.

L-Cysteine-glutathione disulfide is a potential biomarker for curing tuberculosis, present in mammalian cells with hepatoprotective effects, useful in acetaminophen-induced liver toxicity research.

Glutathione sulfinanilide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

Glutathione sodium is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

Glutathione sulfonate is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

Glutathione glycylethyl ester is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

Glutathione maleimide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth.

Glutathione reductase (EC 1.6.4.2) is an enzyme that maintains the supply of reduced glutathione [1].

Glutathione ethyl ester TFA is a glutathione substitute and a cell-permeable glutathione GSH donor that modulates age-related oxidative damage in bovine oocytes, improves the developmental capacity of oocytes from aged cows, and prevents early asthma.

Glutathione ethyl ester acetate is the salt form of Glutathione ethyl ester. Glutathione ethyl ester is an antioxidant and cell-permeable Glutathione (GSH) donor that provides high efficiency of GSH to oocytes and is capable of restoring glutamate-induced oxidative stress and TGase up-regulation and prevent ethanol-induced oxidative stress and apoptosis in cells.

Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (GSSG) by forming a disulfide bridge, while concurrently reducing hydrogen peroxide or lipid peroxides to water, serving as a potent antioxidant and protecting against oxidative stress [1].

Glutathione synthesis-IN-1 (DC-1) is an inhibitor of glutathione synthesis[1].

15-deoxy-Δ12,14-Prostaglandin J2 Glutathione (15-Deoxy-Δ12,14-PGJ2 Glutathione) is a non-enzymatic adduct formed from the reaction of 15-deoxy-Δ12,14-PGJ2 with glutathione. The biological properties of this compound have not yet been determined.

Atrazine-glutathione-conjugate-CoA (Atrazine glutathione conjugate-coenzyme A) is a derivative of coenzyme A.

S-Benzyl-glutathione-CoA (S-Benzyl-glutathione-coenzyme A) is a derivative of coenzyme A.

S-Methyl-glutathione-CoA (S-Methyl-glutathione-coenzyme A) is a derivative of coenzyme A.

Glutathione-CoA, disulfide (Coenzyme A-glutathione mixed disulfide) is a derivative of coenzyme A.

Glutathione-sulfinate-CoA (Glutathione sulfinate-coenzyme A) is a derivative of coenzyme A.

S-(3-Iodobenzyl)glutathione-CoA (S-(3-Iodobenzyl)glutathione-coenzyme A) is a derivative of coenzyme A.

S-Hydroxymethyl-glutathione-CoA (S-Hydroxymethyl glutathione-coenzyme A) is a derivative of coenzyme A.

L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.

Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. Glutathione oxidized can be used to study sickle cells and red blood cells.

Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride targets the mitochondrial inner membrane adenine nucleotidyl transferase (ANT), which inhibits cell proliferation and promotes apoptosis. Glutathione arsenoxide hydrochloride can be used to recognize cell surface proteins such as protein disulfide isomerases.

Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.